Targets | Partner | Discovery | Preclincal | Phase 1 | Phase 2 | |
PRS-346/SGN-BB228 |
4-1BB/CD288 | ✓ | ✓ | ✓ | ||
Candidate Seagen Programs‡ |
n.d. | ✓ |
Pieris and Pfizer (formerly Seagen) Immuno-Oncology Collaboration
This collaboration aims to investigate several targeted, bispecific immuno-oncology treatments for solid tumors and blood cancers. Together, we will develop antibody-Anticalin fusion proteins that leverages Pieris’ suite of agonistic costimulatory Anticalin proteins and Pfizer’s portfolio of cancer targets and tumor-specific antibodies. The bispecific drugs will be designed to activate a patient’s immune cells locally in the tumor microenvironment.
Pipeline Chart
Immuno-Oncology
‡ 2 active bispecific programs in collaboration with Pfizer in addition to PRS-346/SGN-BB228 listed above.
Candidate
PRS-346/SGN-BB228
TARGETS
4-1BB/CD228
PARTNER
PHASE 1
In Progress
Candidate
Candidate Seagen Programs‡
TARGETS
n.d.
PARTNER
DISCOVERY
In Progress
‡ 2 active bispecific programs in collaboration with Pfizer in addition to PRS-346/SGN-BB228 listed above
Candidate
PRS-346/SGN-BB228
TARGETS
4-1BB/CD228
PARTNER
PHASE 1
In Progress
Candidate
Candidate Seagen Programs‡
TARGETS
n.d.
PARTNER
DISCOVERY
In Progress