Careers at Palvella Therapeutics

Job Title: Sr. Manager / Manager, Corporate Development
Location: Wayne, PA / In-Person
Company: Palvella Therapeutics
Reports To: VP of Corporate Development

Position Summary:
We are seeking a highly motivated and analytical Senior Manager or Manager of Corporate Development to join our growing team. This role is ideal for candidates with 2+ years of experience in management consulting or investment banking, particularly within healthcare, biotech, or life sciences. The Sr. Manager / Manager will play a key role in shaping the company’s strategic direction through M&A, licensing, strategic partnerships, new product planning, and investor relations.

Key Responsibilities:
Support evaluation and execution of strategic transactions including M&A, licensing opportunities, joint ventures, and partnerships.

• Conduct financial modeling, valuation analysis, and due diligence to assess potential deals.
• Collaborate with cross-functional teams (R&D, Finance, Clinical, Commercial) to assess strategic fit and integration feasibility.
• Prepare high-quality presentations, memos, and recommendations for executive leadership and the Board of Directors.
• Analyze industry trends, competitive landscape, and pipeline opportunities to inform strategic planning.
• Assist in the development of long-range strategic plans and support corporate fundraising efforts.
• Support investor relations activities, including preparation of earnings materials, investor decks, conference messaging, and engagement with analysts and shareholders to clearly communicate company strategy, performance, and milestones.

Qualifications:
Bachelor’s degree in Business, Finance, Economics, Life Sciences, or related field.

• Minimum 2 years of experience in investment banking, management consulting, or corporate development, ideally with a focus on biotechnology, life sciences, or healthcare.
• Strong financial modeling, valuation, and analytical skills.
• Excellent written and verbal communication skills.
• Ability to work independently and collaboratively in a fast-paced, dynamic environment.
• Passion for biotech innovation and strategic thinking.

Preferred Qualifications:

• Experience working on buy- or sell-side transactions in the life sciences sector.
• Familiarity with biotech R&D, clinical development stages, and regulatory environment.
• Prior exposure to licensing agreements, strategic alliances, or venture investing.

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Job Title: Associate Director, Marketing
Location: Wayne, PA / In-Person
Company: Palvella Therapeutics

Position Summary:

The Associate Director of Marketing will play a critical role in building Palvella’s first commercial brand. This leader will drive core marketing tactics and ensure commercial launch readiness for our inaugural program in mLM. The ideal candidate has experience working in a rare disease where ‘patient finding’ is not simple, and promotional success is accomplished through a combination of innovative digital engagement tactics and in-person sales efforts.  A strong launch track record and a hands-on collaborative style are required.  As the marketing team grows, the role will be tailored, based on the candidate’s experience and professional development interests, to focus on particular stakeholders (e.g., patients/caregivers vs HCPs) or channels (e.g., digital tactics vs field tools).

Key Responsibilities:

• Drive commercial launch readiness, partnering closely with cross‑functional teams across Medical Affairs, Market Access, Field Leadership, Regulatory, and Clinical.
• Manage agency partners to deliver creative, digital, and strategic work aligned to brand goals, including high‑impact disease‑education and product-specific content.  This may include congress materials, digital assets, and field team tools for HCPs, as well as engaging resources and materials for patients/caregivers and other key stakeholders.
• Lead promotional materials through internal approval processes, including medical, legal, and regulatory reviews.
• Incorporate insights from market research and customer interactions into work, and contribute to the evolution of brand strategy, opportunity assessments, and competitive differentiation.
• Oversee project timelines, budgets, and performance tracking across all marketing initiatives.
• Represent Palvella in customer interactions and at medical meetings/conferences.
• Prepare executive‑level presentations and strategic updates for senior leadership.
• Demonstrate high integrity and comply with all laws and company policies.

Location & Work Model
This role is based at Palvella’s headquarters in Wayne, PA. Palvellians work M-Th in the office with flexibility to work from home on Fridays.  Some weekend work and domestic travel, especially when attending medical conferences, should be expected.

Ideal Candidate Snapshot:

• 4+ years of biotech/pharma marketing or other relevant commercial experience.
• Demonstrated success in marketing new product launches, especially first commercial launches, preferred.
• Experience in rare disease, dermatology, and/or vascular anomalies preferred.
• Experience working collaboratively cross-functionally, especially with PRC/MLR and sales teams, preferred.
• Strong cross‑functional collaboration skills and comfort operating in a fast‑paced, high‑accountability environment.
• Strategic thinker with strong analytical skills and ability to navigate ambiguity.
• Experience with omnichannel or digital strategy preferred.

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Job Title: Medical Science Liaison
Location: Wayne, PA / In-Person
Company: Palvella Therapeutics

A Message from the Palvella Leadership Team

Position Summary:

Palvella Therapeutics (NASDAQ: PVLA) is a clinical-stage biopharmaceutical company developing innovative therapies for serious, rare skin and vascular conditions that currently have no FDA-approved therapies. With a pipeline of potentially first-in-disease assets and a clear path toward commercialization, Palvella offers a unique opportunity to join at a pivotal moment, helping bring meaningful therapies to patients with significant unmet medical needs.

At the core of Palvella’s innovation is its patented QTORIN™ platform, which is designed to deliver therapies directly to affected tissue while minimizing systemic exposure. The platform supports the development of topical therapies that penetrate deep into the layers of the skin, reflecting Palvella’s commitment to pairing scientific precision with real-world applicability for patients and clinicians.

Palvella’s lead product candidate, QTORIN™ rapamycin, is being evaluated in clinical programs for microcystic lymphatic malformations (mLM) and cutaneous venous malformations (cVM). With a potential first commercial launch anticipated in early 2027 in mLM, this is a pivotal time to join Palvella, contribute to building its first commercial organization, and make a direct impact on patients, families, and the broader rare skin disease community.

The company is gearing up for what will be a transformational year in 2026 by adding a number of leaders to the management team in preparation for commercialization in early 2027.

The Executive Team

You’ll be joining a passionate, agile, and deeply experienced leadership team, including:

• Wes Kaupinen, Founder and Chief Executive Officer
• Jeff Martini, Ph.D., Chief Scientific Officer
• Matthew Korenberg, Chief Financial Officer
• Ashley Kline, Chief Commercial Officer
• Kathy Goin, Chief Operating Officer
• David Osborne, Ph.D., Chief Innovation Officer

You will report directly to Vimal Patel, Senior Vice President, Medical Affairs

The Role: Medical Science Liaison / Senior Medical Science Liaison

The Medical Science Liaison (MSL) / Senior Medical Science Liaison (Senior MSL) is a field-based medical professional responsible for delivering high-quality, non-promotional scientific exchange and supporting clinical development activities across Palvella’s rare disease portfolio.

The level (MSL vs. Senior MSL) will be determined based on experience, therapeutic expertise, and demonstrated field impact. Both roles are hands-on, externally focused, and deeply connected to the science.

Key Highlights

The successful candidate is scientifically rigorous, externally credible, and deeply patient-focused. He or she will be motivated by advancing meaningful scientific dialogue in areas of high unmet need and by building trusted partnerships within the rare dermatology and vascularanomaly community. This individual will play a visible role in shaping Palvella’s Medical Affairs presence during a pivotal stage of late-stage development and pre-commercial readiness.

• Deliver high-quality, balanced scientific exchange to dermatologists, vascular anomaly specialists, geneticists, and clinical investigators across assigned territory.
• Establish and maintain trusted, long-term relationships with key opinion leaders, academic centers, and vascular anomaly clinics.
• Communicate complex disease biology, mTOR pathway science, and QTORIN™ clinical data with clarity and scientific rigor.
• Support ongoing and planned clinical programs in microcystic lymphatic malformations, cutaneous venous malformations, and other rare dermatologic conditions.
• Generate and share actionable field insights to inform Medical Affairs strategy, clinical development planning, and future launch readiness.
• Partner cross-functionally with Clinical Development, Regulatory, and Commercial colleagues to ensure aligned and compliant scientific engagement.
• Represent Palvella at key dermatology, rare disease, and vascular anomaly congresses and educational forums.
• Contribute to the development and refinement of medical materials, FAQs, and educational content.
• Maintain deep, current knowledge of mTOR biology and emerging data in rare dermatologic and vascular disorders.
• Play a visible role in building a high-performing, collaborative Medical Affairs organization during a pivotal stage of company growth.

Location & Work Model

This is a field-based, externally focused role with significant travel (approximately 60–70%) to support scientific engagement with key opinion leaders, investigators, and academic centers across the assigned territory. The MSL will operate remotely within the United States while maintaining strong alignment with cross-functional partners.

Palvella’s headquarters is located in suburban Philadelphia (Wayne, PA), and periodic travel to headquarters and national congresses will be expected.

Ideal Candidate Snapshot

• Advanced scientific degree (PharmD, MD, PhD, NP, PA, or equivalent) with strong foundational knowledge in dermatology, rare disease, immunology, vascular anomalies, or related therapeutic areas.
• 3–5+ years of experience in Medical Affairs or as a field-based MSL (level determined by experience), preferably supporting clinical-stage or pre-launch assets.
• Demonstrated ability to engage in high-level, evidence-based scientific exchange with dermatologists, academic investigators, and multidisciplinary specialty clinics.
• Experience working with or strong interest in rare disease populations, complex care models, and academic medical centers.
• Proven track record of building credible, trusted external relationships while maintaining compliance and scientific integrity.
• Strong ability to distill complex clinical and mechanistic data into clear, impactful dialogue tailored to diverse stakeholders.
• Collaborative mindset with experience partnering cross-functionally across Clinical Development, Regulatory, and Commercial teams.

Apply Now