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The Power of QTORIN™

Palvella’s proprietary QTORIN™ technology was developed over several years of research to overcome inherent challenges with topical delivery of mTOR inhibitors such as rapamycin – including chemical stability, skin penetration, and skin distribution. QTORIN™ is an anhydrous gel comprising excipients precisely selected in an optimized ratio to achieve drug stability at room temperature and enable cutaneous distribution into the keratinocytes in the basal layer of the epidermis and to the reticular dermis, where the pathology manifests in many dermatologic conditions. Two of Palvella’s programs, PTX-022 and PTX-367, leverage QTORIN™ to deliver the active agent directly to the root genetic cause of each disease. QTORIN™ offers potential applicability to a wide range of diseases and therapeutic agents, including single agents and combination therapies.

How QTORIN Works