Everyone suffering from a rare genetic skin disease deserves a treatment.
Palvella (pɑlʋelːɑ): a Finnish word meaning “serve”
Palvella Therapeutics aims to help every individual suffering from rare genetic skin diseases find a treatment. Founded in 2015, Palvella’s team of passionate, highly credentialed collaborators is dedicated to making transformative new treatments a reality for thousands.
Our Vision
Imagine a future where people suffering from serious, rare skin diseases—and the physicians that treat them—have more options than ever before.
Our vision, supported by our mission of serving patients, is to become the leading rare disease biopharmaceutical company focused on developing and (if approved) commercializing novel therapies for serious, rare skin diseases for which there are no approved therapies.
Our Approach
Building upon our years of experience in rare diseases to become the leader in the development and commercialization of therapies for rare genetic skin diseases.
More than 98% of the reported 597 rare skin diseases do not have a therapy approved by the FDA. Serious, rare genodermatoses represent a substantial opportunity to develop and, if approved, commercialize first-in-disease therapies. Our goal is to select diseases caused by genetic mutations with a well-understood etiology and a strong rationale for a specific pathway intervention, many of which have a debilitating, lifelong impact on individual lives.
Forge meaningful patient advocacy collaborations.
We take a rigorous, systematic approach to understanding the impacts of the diseases we address. By creating meaningful collaborations with disease advocacy organizations and patients, we can learn more about what constitutes clinical meaningfulness and acceptable risk-benefit. These learnings significantly inform our product development approach, which may contribute to the regulatory acceptability of our product candidates.
Maximize the potential of the QTORIN™ platform across a wide range of molecules.
We intend to further leverage our scalable QTORIN™ platform to generate additional product candidates that target the known causes of serious, rare genodermatoses.
Our Team
Leadership
Mr. Kaupinen brings more than 20 years of entrepreneurial life sciences experience as an operating executive, early-stage investor, including having worked closely with several companies that have secured FDA approvals of novel treatments for high unmet indications. Prior to Palvella, Mr. Kaupinen served as Senior Vice President of Corporate Development and Commercialization at Insmed (NASDAQ: INSM), a global commercial stage biopharmaceutical company focused on rare diseases. Previously, Mr. Kaupinen was a Principal at Quaker Partners, a life sciences venture capital firm with $700mm under management, where he worked on several public and private investments, including recruiting new leadership to Insmed to execute on a rare disease strategy. Mr. Kaupinen has served as a board director or observer for more than 10 companies, including leading Series A investments in Intact Vascular and TELA Bio (NASDAQ: TELA). Mr. Kaupinen earned an M.B.A. from the Wharton School of the University of Pennsylvania, and a B.A. in Economics from the University of Virginia.
Mr. Korenberg is a seasoned executive with significant operational and financial leadership experience in the healthcare industry. Prior to Palvella, he served as President and Chief Operating Officer of public biotechnology company Ligand Pharmaceuticals Incorporated (Nasdaq: LGND) since November 2022 and, prior to that, as the company’s Chief Financial Officer since August 2015. Prior to Ligand Pharmaceuticals, Mr. Korenberg was the founder, Chief Executive Officer, and a director of NeuroCircuit Therapeutics, a company focused on developing drugs to treat genetic disorders of the brain with an initial focus on Down syndrome. Prior to founding NeuroCircuit Therapeutics, Mr. Korenberg served as a Managing Director and member of the healthcare investment banking team at The Goldman Sachs Group from July 1999 to August 2013. During his 14-year tenure at Goldman Sachs, Mr. Korenberg focused on advising and financing companies in the biotechnology and pharmaceutical sectors. Mr. Korenberg has served on the board of multiple public and private companies and currently serves on the board of directors, including the audit committee, of Lifecore Biomedical Inc. (NASDAQ: LFCR), a fully integrated contract development and manufacturing organization. He earned a B.B.A. in Finance and Accounting from the University of Michigan.
Dr. Martini brings nearly 20 years of leadership roles in R&D and corporate development.
Prior to Palvella, Dr. Martini served as Executive Director of Business Development and Corporate Strategy at Marinus Pharmaceuticals, a biopharmaceutical company developing novel therapeutics for rare diseases. Previously, Dr. Martini was Project Champion at Teva Specialty Pharmaceuticals and Cephalon Pharmaceuticals where he led the cross-functional development teams for several therapeutic areas and was responsible for program strategy and delivery. Prior experiences include research scientist roles at GSK and Centocor and as an investment consultant at Ben Franklin Technology Partners where he led the due diligence for early stage investments. Dr. Martini has experience leading programs at all stages of development, including IND submission through NDA approval and product launch. Dr. Martini holds a B.S. from Penn State University and a Ph.D. in molecular pharmacology from Jefferson University.
With a positive and relentless spirit, Ms. Goin builds and coaches high-performing and successful clinical development teams.
Since 1998, Ms. Goin served many patient populations by developing drugs and devices to treat different cancers, heart disease/abnormalities, and pain conditions. As Vice President, Clinical Operations at Trevena, Inc., she shaped trial execution strategies across all programs by promoting meaningful and streamlined interactions between sites and sponsor representatives and employing modern processes for lean yet highly effective trial execution. These approaches led to helping the company start and finish three Phase III studies in just under two years. In 2017, she joined colleagues to start Clinical Works, a progressive specialty consulting firm focused on helping emerging and small biotech/pharmaceutical companies start their clinical programs and execute trials. Ms. Goin holds a Master of Science in Occupational Therapy from College Misericordia.
Dr. Shroot brings over 30 years of experience in drug research and development specializing in skin disorders, and played a key role in the development of commercially available therapeutics including Differin, Atralin, Vectical, and Diflucan.
Dr. Shroot is the recipient of the American Skin Association’s Lifetime Achievement Award and an honorary lifetime member of the Society for Investigative Dermatology. Prior to Palvella, Dr. Shroot held senior roles in the biopharma industry, including President of Galderma Research, Chief Scientific Officer of Barrier Therapeutics (sold to Stiefel), and CSO/VP of R&D for DFB Pharmaceuticals. Dr. Shroot also served as the chief executive officer of Signum Biosciences, a company developing dermatological therapeutics. Dr. Shroot is an inventor on over 50 patents, author of over 260 publications, and a member of the editorial boards of several prestigious dermatology journals. Dr. Shroot earned a B.Sc. in Chemistry and a Ph.D. in Organic Chemistry from Glasgow University in Scotland.
Ms. Cook’s 15-year career spans large and small pharmaceutical companies where she has managed clinical development programs for clinical and commercial stage products.
Prior to Palvella, Ms. Cook served as Director of Clinical Operations for Complexa, a clinical stage biopharmaceutical company focused on life-threatening fibrosis and inflammatory diseases. Prior to joining Complexa, she served as the Director of Clinical Operations for Trevena, Inc., where she contributed to the completion of multiple Phase 1 through Phase 3 clinical trials. Emily also held clinical and sales roles at Applied Clinical Intelligence, Yaupon Therapeutics, and Sanofi-Aventis Pharmaceuticals. Emily received her B.A. in Microbiology from Miami University and earned her Clinical Research Associate certification from the Association of Clinical Research Professionals.
Ms. Kampf joins Palvella from Marinus Pharmaceuticals, where she served as Executive Director of Regulatory Affairs. While at Marinus, Ms. Kampf was responsible for leading an NDA for a novel therapy targeting a rare genetic disease that had been granted orphan, rare pediatric disease, and fast track designations. Upon submission of the NDA, the FDA granted the application priority review, and it was approved by the FDA in the first review cycle. Ms. Kampf also spearheaded the product’s global expansion, with MAAs submitted and approved outside the U.S. in the EU and the UK.
Beyond her work at Marinus, Ms. Kampf gained extensive experience in marketing application preparation, submission, and approvals at Braeburn Pharmaceuticals, Cephalon/Teva, and Neuromed. Notably, during her tenure at Teva Pharmaceuticals, Ms. Kampf led a BLA for the treatment of asthma, resulting in the successful review and approval of applications in both the U.S. and EU (pre-Brexit).
Throughout her 17-year career, Ms. Kampf has supported the global development and registration of multiple medicinal products across a broad range of therapeutic areas, leading several successful interactions with the FDA and EMA. Additionally, Ms. Kampf brings considerable experience in the life-cycle management of approved applications and in the strategy, preparation, and conduct of FDA advisory committee meetings.
Ms. Kampf earned a Master of Science in Biological Sciences from Drexel University and a Bachelor of Arts in Anthropology from the University of Miami (FL).
Ms. Wei joined Palvella in December 2024. She was most recently a Principal in Centerview Partners’ Healthcare practice, where she advised life sciences clients on a broad range of complex strategic and financial issues and transactions, including mergers, acquisitions, partnerships, defense, and financings. Over the course of her six years at Centerview, she advised on transactions exceeding $90 billion in total deal value. She began her career in the healthcare investment banking group at Cowen & Company.
Ms. Wei is a graduate of the Roy and Diana Vagelos Program in Life Sciences & Management (LSM) at the University of Pennsylvania with a Bachelor of Arts in Mathematical Biology and a Bachelor of Science in Economics from The Wharton School.
Board of Directors
From 1987 to 2005, Mr. Jenkins was a general partner of Apax Partners, a leading global private equity firm where he served as chief operating officer overseeing a multi-billion dollar venture capital and private equity investment portfolio. Since 2006, Mr. Jenkins has been an active private investor primarily funding technology-based start-ups. Mr. Jenkins has been or currently serves as a board member of numerous public and private companies, including SkinMedica (acquired by Allergan), Colorescience, Flower Orthopedics, Power Survey, Sunglass Hut, and Spyder Active Sports. Prior to joining Apax, Mr. Jenkins was a banker managing banking facilities in Europe. Mr. Jenkins earned a B.A. in Economics and Accounting from Lafayette College where he currently serves as a Trustee.
Mr. Davis is a founding Managing Director at HealthCare Royalty Partners, a global healthcare investment firm. He has 30 years of experience working in and investing in the pharmaceutical and biotechnology industries. Over the course of his career, Mr. Davis has been involved in over $2 billion in healthcare deals and nearly $1 billion in royalty financings. He has also led, structured and closed over 40 additional intellectual property licenses, as well as growth equity, and debt deals. Previously, Mr. Davis was a partner at Paul Capital Partners, where he co-managed that firm’s royalty investments as a member of the royalty management committee. He also served as a partner responsible for biopharmaceutical growth equity investments at Apax Partners. Prior to beginning his principal investment career in 2001, Mr. Davis held various sales and product management roles at Abbott Laboratories and worked in business development, operations and licensing at Elan Pharmaceuticals. Mr. Davis holds a B.S. from the U.S. Naval Academy and an M.B.A. from Harvard University. He currently serves on the board of Ligand Pharmaceuticals (NASDAQ: LGND).
Tadd S. Wessel is the founder and Managing Partner of Petrichor. Mr. Wessel was formerly a Managing Director at OrbiMed Advisors, where he led the build-out of the healthcare special situations and structured finance business. Prior to OrbiMed, Mr. Wessel was a Vice President in the Drawbridge Special Opportunities Fund at Fortress Investment Group, focused on healthcare investments. Mr. Wessel began his career in investment banking at Robertson Stephens, where he worked in the life sciences group. Mr. Wessel holds an A.B. in Biology from Princeton University.
Mr. Kaupinen brings more than 20 years of entrepreneurial life sciences experience as an operating executive, early-stage investor, including having worked closely with several companies that have secured FDA approvals of novel treatments for high unmet indications. Prior to Palvella, Mr. Kaupinen served as Senior Vice President of Corporate Development and Commercialization at Insmed (NASDAQ: INSM), a global commercial stage biopharmaceutical company focused on rare diseases. Previously, Mr. Kaupinen was a Principal at Quaker Partners, a life sciences venture capital firm with $700mm under management, where he worked on several public and private investments, including recruiting new leadership to Insmed to execute on a rare disease strategy. Mr. Kaupinen has served as a board director or observer for more than 10 companies, including leading Series A investments in Intact Vascular and TELA Bio (NASDAQ: TELA). Mr. Kaupinen earned an M.B.A. from the Wharton School of the University of Pennsylvania, and a B.A. in Economics from the University of Virginia.
Mr. Kiritsy is founder and managing member of Precision Kapital, LLC, a private investment and advisory firm. Prior to forming Precision Kapital, Mr. Kiritsy teamed up with the late pharmaceutical legend, Michael Jaharis, to co-found Arisaph Pharmaceuticals and served as Arisaph’s President and Chief Executive Officer from 2005 through 2018. Prior to Arisaph, Mr. Kiritsy served as Executive Vice President, Corporate Development and Chief Financial Officer of Kos Pharmaceuticals, Inc., where he played a key operating role in building the company from start-up to highly profitable, publicly traded, commercial company, in which Kos internally developed and commercialized the blockbuster Niaspan® franchise. Mr. Kiritsy spearheaded more than 10 major corporate development transactions and raised approximately $500 million in public equity, including Kos’ initial public offering. Kos was acquired by Abbott Laboratories for $3.7 billion in 2016. Additionally, Mr. Kiritsy has broad corporate governance experience, previously serving as board member and various committee chairs of multiple public and private companies. Mr. Kiritsy also serves as an advisor to Red Sky Partners, LLC. Mr. Kiritsy is a seasoned entrepreneur, who possesses 30 years of industry experience, building emerging biopharmaceutical companies with expertise in R&D, business development and finance.
Elaine J. Heron, Ph.D. rejoined our Board in December 2024. She previously served on our Board from July 2018 to August 2022. From February 2009 to October 2015, Dr. Heron served as Chair and CEO of Amplyx Pharmaceuticals, Inc., a private drug development company acquired by Pfizer, Inc. in April 2021.
Dr. Heron currently serves on the boards of BioMarin Pharmaceutical Inc. (BMRN), a commercial stage company with eight marketed products including seven with orphan designation, Vaxart, Inc. (VXRT), a public clinical-stage biotechnology company which is developing oral vaccines, Visgenx, Inc., a private early-stage ophthalmology company, BlueWhale Bio, a private early-stage company developing products for cell therapy manufacturing, and Watershed Therapeutics, Inc., a private early-stage urology company. Dr. Heron is also an advisor to K2X Technology and Life Science, Inc., a FinTech company developing a vehicle for investing in early-stage companies.
From July 2001 to October 2008, Dr. Heron was Chair and CEO of Labcyte Inc., a private biotechnology tools company. Before joining Labcyte Inc., she spent six years in positions of increasing responsibility at the Applied Biosystems Group of Applera Corporation, a biotechnology tools company, including the positions of General Manager and Vice President of Sales and Marketing.
Dr. Heron holds a B.S. in Chemistry with highest distinction and a Ph.D. in Analytical Biochemistry from Purdue University and an M.B.A. from Pepperdine University.
Medical and Scientific Advisory Board
David Bickers, M.D.
Chair of Dermatology
Columbia University
Alain Hovnanian, M.D., Ph.D.
Team Lead
Imagine Institute
Sancy Leachman, M.D., Ph.D.
Chair of Dermatology
Oregon Health & Science University
Will Motley, M.D.
Johns Hopkins & Third Rock Ventures
Edel O’Toole, M.D., Ph.D.
Academic Dermatologist
Barts and The London
Amy S. Paller, M.D.
Chair, Department of Dermatology · Director, Skin Biology and Diseases Resource-Based Center
Walter J. Hamlin Professor of Dermatology
Northwestern Medicine
Joyce Teng, M.D., Ph.D.
Professor of Dermatology
Stanford University
James Treat, M.D.
Associate Professor of Clinical Pediatrics and Dermatology
Children’s Hospital of Philadelphia